Telomerase, because of its role in cancer and aging, has long been a target of drug companies who want to block it to stop the uncontrolled cell growth characteristic of cancer, or boost it to create a fountain of youth. The structure of the enzyme complex has been a mystery, however, until now. Scientists have finally obtained a detailed picture of the architecture of the RNA-protein complex, a breakthrough for drug design.
Long-sought structure of telomerase paves way for new drugs for aging, cancer
Science Daily - 25 Apr 2018 19:18
Telomerase, because of its role in cancer and aging, has long been a target of drug companies who want to block it to stop the uncontrolled cell growth characteristic of cancer, or boost it to create a fountain of youth. The structure of the enzyme complex has been a mystery, however, until now. Scientists have finally obtained a detailed picture of the architecture of the RNA-protein complex, a breakthrough for drug design.
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